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S6377 Sigma-Aldrich

Sulfisoxazole

≥99.0%

Synonym: 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide, N1-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide, Sulfafurazole

  • CAS Number 127-69-5

  • Empirical Formula (Hill Notation) C11H13N3O3S

  • Molecular Weight 267.30

  •  Beilstein/REAXYS Number 6737262

  •  EC Number 204-858-9

  •  MDL number MFCD00003150

  •  PubChem Substance ID 24899697

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Properties

Related Categories Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
InChI Key   NHUHCSRWZMLRLA-UHFFFAOYSA-N
assay   ≥99.0%
solubility   acetone: complete 50 mg/ml
  10% HCl: complete 33 mg/mL, clear, colorless to faintly yellow
  alcohol: slightly soluble
  chloroform: insoluble
originator   Roche
storage temp.   2-8°C
Gene Information   rat ... Ednra(24326)

Description

Application

Sulfisoxazole was one of the antibiotics tested on bacterial reporter panel that gave information on pollution load on the environment.11

Biochem/physiol Actions

Sulfisoxazole, a sulfonamide, is an antibacterial agent that acts by inhibiting the folic acid metabolism.1 It is also a non-selective endothelin antagonist. It is effective in the treatment of recurrent acute otitis media and also in rendering protection to retina against ischemic-like insults.2,3

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 
2
RTECS 
WO9100000

Documents

Certificate of Analysis

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Certificate of Origin

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Making Headway

Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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