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S7388 Sigma-Aldrich

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide

Synonym: N-Succinyl-Ala-Ala-Pro-Phe-pNA, N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide

  • CAS Number 70967-97-4

  • Empirical Formula (Hill Notation) C30H36N6O9

  • Molecular Weight 624.64

  •  Beilstein/REAXYS Number 4289896

  •  MDL number MFCD00077161

  •  PubChem Substance ID 24899742

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Description

Amino Acid Sequence

N-Suc-Ala-Ala-Pro-Phe-pNA

Application

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used as a substrate to determine chymotrypsin activity.

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used:
• as a substrate for cathepsin G assay in bone marrow lysates.
• in proteolytic activity assay of serine protease subtilisin carlsberg (SC).
• as a substrate for neutrophil elastase, trypsin and chymotrypsin in protease assay.

Packaging

25, 100, 250, 500 mg in poly bottle

Biochem/physiol Actions

N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a substrate for subtilisin and proteases.

Substrates

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a colorimetric substrate for chymotrypsin, human leukocyte cathepsin G and peptidyl prolyl isomerase.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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