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S7448 Sigma-Aldrich

STF-62247

≥98% (HPLC), solid

Synonym: N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine

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Properties

Related Categories Apoptosis Inducers, Apoptosis and Cell Cycle, Autophagy, Autophagy Activators, Bioactive Small Molecule Alphabetical Index,
InChI Key   KATNUHQNJGNLPW-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
solubility   DMSO: soluble 26 mg/mL
  H2O: insoluble
storage temp.   room temp

Description

Packaging

5 mg in glass bottle

Application

STF-62247 may be used as positive control in autophagy inducing cell signaling studies.

Biochem/physiol Actions

STF-62247 induces the formation of large vacuoles in the von Hippel-Lindau deficient renal carcinoma cells, a characteristic of autophagy.1

STF-62247 is a selective inducer of autophagy in VHL-deficient renal cell carcinoma cells.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis


Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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