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S8752 Sigma-Aldrich

Succinylsulfathiazole

≥98%

  • CAS Number 116-43-8

  • Empirical Formula (Hill Notation) C13H13N3O5S2

  • Molecular Weight 355.39

  •  Beilstein/REAXYS Number 349989

  •  EC Number 204-141-0

  •  MDL number MFCD00022437

  •  PubChem Substance ID 24899811

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Properties

Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Mechanism of Action,
InChI Key   SKVLYVHULOWXTD-UHFFFAOYSA-N
assay   ≥98%
form   powder
color   white to off-white
solubility   1 M NaOH: soluble 50 mg/mL
Mode of action   DNA synthesis | interferes
  enzyme | inhibits
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria

Description

General description

Chemical structure: sulfonamide

Packaging

100, 500 g in glass bottle

Application

Succinylsulfathiazole is used to block the synthesis of folic acid. It is used to study folate deficiency. It is used to suppress folate production by bacteria in the intestine.

Biochem/physiol Actions

Succinylsulfathiazole is a competitive inhibitor of dihydropteroate synthetase. It is a dihydrofolate reductase (DHFR) inhibitor.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. S8752.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
WM4767000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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