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  • SAB5600047 - Anti-BRAF (V600E) antibody, Rabbit monoclonal

SAB5600047 Sigma-Aldrich

Anti-BRAF (V600E) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM8, purified immunoglobulin



Related Categories Alphabetical Index, Antibodies, BL-BZ, Primary Antibodies, Recombinant Rabbit Monoclonal Antibodies More...
clone   RM8, monoclonal
  recombinant monoclonal
application(s)   ELISA: 0.5-2 μg/mL
  immunoblotting: 0.5-2 μg/mL
  immunocytochemistry: 0.5-5 μg/mL
  immunohistochemistry: 0.5-5 μg/mL
species reactivity   human
form   buffered aqueous glycerol solution
shipped in   wet ice
storage temp.   −20°C
antibody form   purified immunoglobulin
isotype   IgG
antibody product type   primary antibodies
recombinant   expressed in HEK 293 cells
concentration   ~1 mg/mL
NCBI accession no.   673
UniProt accession no.   P15056


General description

BRAF (B-Raf proto-oncogene) is a serine-threonine kinase, that codes for B-Raf protein. It is located on human chromosome 7q34.


This antibody reacts to the BRAF V600E mutant. No cross reactivity with wild type BRAF.


Peptide corresponding to BRAF V600E mutant

Physical form

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

BRAF (B-Raf proto-oncogene) participates in signaling direct cell growth. It induces tumor growth by initiating the mitogen-activated protein kinase (MAPK) pathway in various tumors like cutaneous melanoma and carcinomas of the thyroid and colon.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Safety & Documentation

Safety Information

NONH for all modes of transport
Protocols & Articles


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