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SMB00706 Sigma-Aldrich

Lycopene

≥98% (HPLC), from tomato

Synonym: ψ,ψ-Carotene, 2,6,10,14,19,23,27,31-Octamethyl-dotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene

  • CAS Number 502-65-8

  • Empirical Formula (Hill Notation) C40H56

  • Molecular Weight 536.87

  •  MDL number MFCD00017350

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Properties

Related Categories Antioxidant and Free Radical Scavengers, Cancer Research, Carotenoid, Cell Biology, Chemopreventive Agents,
Quality Level   200
InChI Key   OAIJSZIZWZSQBC-GYZMGTAESA-N
assay   ≥98% (HPLC)
form   powder
storage condition   protect from light
solubility   THF: 1 mg/mL
  chloroform: 5 mg/mL
shipped in   dry ice
storage temp.   −20°C

Description

General description

Lycopene is a carotenoid found in many red fruits and vegetables such as watermelon, pink guava, and tomato. Lycopene is a potent antioxidant. It is suggested that lycopene is used by the plant to protect against reactive oxygen species (ROS).

Biochem/physiol Actions

Antioxidant micronutrient of tomatoes associated with decreased risk for cancer and cardiovascular disease. Enhances gap juction communication between cells via upregulation of connexin 43 and reduces proliferation of cancer cells in culture. Inhibits cholesterol synthesis and enhances low-density lipoprotein degradation.

Lycopene has been found to be active against oral cancer and to inhibit metastasis of human liver adenocarcinoma cells by down regulation of NOX4. Lycopene was also found to be a beneficial supplement for people with cardiovascular diseases.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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