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SML0012 Sigma-Aldrich

SBE 13 hydrochloride

≥98% (HPLC)

Synonym: N-(4-((6-Chloro-3-pyridinyl)methoxy)-3-methoxybenzyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)amine; N-[[4-[(6-Chloro-3-pyridinyl)methoxy]-3-methoxyphenyl]methyl]-3,4-dimethoxy-benzeneethanamine hydrochloride

  • CAS Number 1052532-15-6

  • Empirical Formula (Hill Notation) C24H27ClN2O4·HCl

  • Molecular Weight 479.40

  •  MDL number MFCD20036266

  •  PubChem Substance ID 329825088

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology,
InChI Key   QBGSVDJLQQXEGG-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
color   white to tan
solubility   DMSO: ≥17 mg/mL
storage temp.   2-8°C

Description

Application

SBE 13 hydrochloride may be used in cell signaling studies.

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

SBE13 is a cell-permeable highly potent polo-like kinase (Plk1) inhibitor that targets the inactive conformation of the kinase. SBE13 does not effect the activity of Plk2, Plk3, Aurora A kinases.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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