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SML1030 Sigma-Aldrich

HENA

≥98% (HPLC)

Synonym: (3b,20b)-3-Hydroxy-olean-12-en-29-oic acid sodium salt

  • CAS Number 1148013-87-9

  • Empirical Formula (Hill Notation) C30H47NaO3

  • Molecular Weight 478.68

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, H,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 3 mg/mL, clear (warmed)
storage temp.   room temp

Description

General description

3-Hydroxyolean-12-en-30-oate (HENA) is a triterpenoid. It is a non steroidal compound having structural similarities with lithocholic acid, a cholane steroid.

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

HENA (3-Hydroxyolean-12-en-30-oate) specifically activates large conductance, voltage- and Ca2+-gated K+ (BK) channels containing KCNMB1 (β1) subunits (EC50 = 53 μM). BK/β1 channels are expressed predominantly in smooth muscle. HENA induces vasodilation in rodent models.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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