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SML1062 Sigma-Aldrich

6-Aminophenanthridine

≥98% (HPLC)

Synonym: 6-Amino-phenanthridine, 6AP

  • CAS Number 832-68-8

  • Empirical Formula (Hill Notation) C13H10N2

  • Molecular Weight 194.23

  •  NACRES NA.77

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Properties

Related Categories A-AM, Alzheimer′s Disease, Assays/Reagents for Alzheimer′s Disease Research, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to brown
solubility   DMSO: 20 mg/mL, clear
storage temp.   2-8°C
InChI   1S/C13H10N2/c14-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)15-13/h1-8H,(H2,14,15)
InChI key   FVCXJXKLDUJOFA-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

6-Aminophenanthridine selectively inhibits protein folding activity of the ribosome (PFAR). Apparently 6-Aminophenanthridine interacts with the ribosome domain V rRNA and the protein substrate. 6-Aminophenanthridine is an antiprion compound that promotes mammalian prion clearance.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Discover Bioactive Small Molecules for Neuroscience

The nervous system, comprised of the brain and spinal cord (central nervous system, or CNS) and network of nerves that connects the CNS to the rest of the body (peripheral nervous system, or PNS) is ...
Keywords: Bioactive small molecules, Central Nervous System, Diseases, Metabolism, Neurodegenerative Diseases, Neuroscience, Neurotransmission, Neurotransmitters

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