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SML1156 Sigma-Aldrich

NID-1

≥98% (HPLC)

Synonym: N-(2-Ethylphenyl)-3-(5-nitro-2-thienyl)- 2-propenamide

  • CAS Number 476316-58-2

  • Empirical Formula (Hill Notation) C15H14N2O3S

  • Molecular Weight 302.35

  •  PubChem Substance ID 329825686

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Properties

Related Categories Apoptosis Inducers, Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
InChI Key   YTQHWWVZNNZOIK-VQHVLOKHSA-N
assay   ≥98% (HPLC)
form   powder
color   faintly yellow to dark yellow
solubility   DMSO: 25 mg/mL, clear
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

NID-1 (Novel Inducer of Death-1) is a cell permeable and potent inducer of energy-dependent non-apoptotic cell death in mammalian cell lines. NID-1 induced cell death is distinct from macroautophagy, but still reacquires ATG5 and the lysosomal hydrolase cathepsin-L.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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