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SML1363 Sigma-Aldrich

IHR-1

≥98% (HPLC)

Synonym: N,N′-1,4-Phenylenebis(2,5-dichlorobenzamide), N,N′-1,4-Phenylenebis[2,5-dichloro-benzamide]

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Properties

Related Categories Angiogenic Factors, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 10 mg/mL, clear
storage temp.   2-8°C
SMILES string   O=C(C1=C(Cl)C=CC(Cl)=C1)NC2=CC=C(NC(C3=CC(Cl)=CC=C3Cl)=O)C=C2
InChI   1S/C20H12Cl4N2O2/c21-11-1-7-17(23)15(9-11)19(27)25-13-3-5-14(6-4-13)26-20(28)16-10-12(22)2-8-18(16)24/h1-10H,(H,25,27)(H,26,28)
InChI key   VCLHHRGZKNUOAQ-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

IHR-1 (inhibitor of hedgehog response 1) is a potent cell-membrane-impermeable Smo antagonist. IHR-1 blocks hedgehog induced movement of Smo into the primary cilium.

Safety & Documentation

Safety Information

Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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