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SML1500 Sigma-Aldrich

Spadin trifluoroacetate salt

≥95% (HPLC)

Synonym: L-Tyrosyl-L-alanyl-L-prolyl-L-leucyl-L-prolyl-L-arginyl-L-tryptophyl-L-serylglycyl-L-prolyl-L-isoleucylglycyl-L-valyl-L-seryl-L-tryptophylglycyl-L-leucyl-L-arginine, YAPLPRWSGPIGVSWGLR

  • CAS Number 1270083-24-3 (free base)

  • Empirical Formula (Hill Notation) C96H142N26O22 · xC2HF3O2

  • Molecular Weight 2012.32 (free base basis)

  •  NACRES NA.77

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Description

Packaging

1 mg in glass bottle

Biochem/physiol Actions

Spadin is a brain penetrant TREK-1 channel inhibitor that has antidepressant effects in mouse models of depression with a rapid onset of action.

Spadin is a peptide derived from a propeptide released in blood upon Sortilin modification.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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