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SML1544 Sigma-Aldrich

VPC-14228

≥98% (HPLC)

Synonym: 2-Morpholino-4-phenylthiazole, 4-(4-Phenyl-2-thiazolyl)-morpholine, 4-(4-Phenylthiazol-2-yl)morpholine

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Properties

Related Categories Androgen, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   MRNNJVNMXOZEQC-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 20 mg/mL, clear
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR) that binds to AR DNA-binding domain (AR DBD). Apparently VPC-14228 blocks the transcriptional activity of constitutively active AR splice variants.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis


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Protocols & Articles
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