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SML1548 Sigma-Aldrich

THPN

≥98% (HPLC)

Synonym: 1-(2,4,6-Trihydroxyphenyl)-1-nonanone, 1-(3,4,5-Trihydroxyphenyl)nonan-1-one, CID 3063200

  • CAS Number 100079-26-3

  • Empirical Formula (Hill Notation) C15H22O4

  • Molecular Weight 266.33

  •  PubChem Substance ID 329825957

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Gene Regulation,
InChI Key   NVFRHTFJDGAFQS-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 25 mg/mL, clear
storage temp.   2-8°C

Description

Other Notes

air sensitive

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

THPN is potent nuclear receptor TR3 (Nur77) antagonist that induces autophagic cell death in melanoma. Co-application of THPN with Akt2 inhibitors significantly represses tumor growth in xenograft mouse model.

General description

THPN or 1-(3,4,5-Trihydroxyphenyl)nonan-1-one, is a derivative of cytosporone B.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis


Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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