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SML1754 Sigma-Aldrich

CTX1

≥95% (HPLC)

Synonym: 3,6-Diamino-9-acridinecarbonitrile, NSC 363260

  • CAS Number 501935-96-2

  • Empirical Formula (Hill Notation) C14H10N4

  • Molecular Weight 234.26

  •  NACRES NA.77

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Properties

Related Categories Apoptosis Inhibitors, Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, CI-CZ,
Quality Level   100
assay   ≥95% (HPLC)
form   powder
color   , faint to very dark red
solubility   DMSO: 15 mg/mL, clear
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

CTX1 is a potent HdmX inhibitor that overcomes HdmX-mediated p53 repression. CTX1 inhibits proliferation and induces apoptosis in number of cancer cell lines. CTX1 inhibits growth of primary human AML in immunodeficient mice.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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