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SML1758 Sigma-Aldrich

Tetrazanbigen

≥98% (HPLC)

Synonym: 5,6,13,14-Tetrahydro-4bH-6,7,12,12b-tetraaza-benzo[b]chrysene, TNBG

  • Empirical Formula (Hill Notation) C18H16N4

  • Molecular Weight 288.35

  •  PubChem Substance ID 329826056

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Properties

Related Categories Apoptosis Inducers, Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 5 mg/mL, clear (warmed)
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Tetrazanbigen (TNBG) is a potent and selective antitumor drug that induces lipid accumulation in cancer cells. Tetrazanbigen induces S phase arrest and apoptosis in hepatocellular carcinoma QGY-7701. Tetrazanbigen potently inhibits growth of QGY-7701 cells xenografts in mice.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Protocols & Articles
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