SML1780 Sigma-Aldrich


≥98% (HPLC)

Synonym: N4-[1-[[4-(1,1-Dimethylethyl)phenyl]methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide

  • CAS Number 1799759-24-2

  • Empirical Formula (Hill Notation) C27H25F4N5O2

  • Molecular Weight 527.51

  •  PubChem Substance ID 329826061



Related Categories B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 20 mg/mL, clear
storage temp.   2-8°C
SMILES string   FC1=CC=C2C(N=C(C(N)=O)C=C2C(NC3=C(C)N(CC4=CC=C(C(C)(C)C)C=C4)N=C3C(F)(F)F)=O)=C1



5, 25 mg in glass bottle

Biochem/physiol Actions

BAY-588 is an inactive control probe for BAY-876. BAY-876 is a potent, highly selective, cell-permeable inhibitor of glucose transporter GLUT1. For characterization details of BAY-876 and BAY-588, please visit the BAY-876 probe summary on the Structural Genomics Consortium (SGC) website.

BAY-876, the active GLUT1 probe, is available from Sigma. To learn more about and purchase BAY-876, click here.

To learn about other SGC chemical probes for protein targets, visit

Features and Benefits

BAY-588 is a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit

This compound is a featured product for Nitric Oxide & Cell Stress research. Click here to discover more featured Nitric Oxide & Cell Stress products. Learn more about bioactive small molecules for other areas of research at

Safety & Documentation

Safety Information

Hazard statements 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Protocols & Articles


Discover Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

Exposure to harsh conditions, cellular damage, and other factors can cause stress on cells. Stress attributed directly and indirectly to oxygen is referred to as oxidative stress, which is imposed on...
Keywords: Antimicrobials, Bioactive small molecules, Cancer, Diseases, Neurodegenerative Diseases, Oxidations

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