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SML1894 Sigma

SYP-5

≥98% (HPLC)

Synonym: (2E)-1-(5-Hydroxy-2-2-dimethyl-2H-1-benzopyran-6-yl)-3-(2-thienyl)-2-propen-1-one, (E)-1-(5-Hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(thio-phen-2-yl)prop-2-en-1-one

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DNA-RNA Transcription Regulators,
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 20 mg/mL, clear
storage temp.   2-8°C

Description

Biochem/physiol Actions

SYP-5 is potent and selective inhibitor of HIF-1 activity that decreases HIF-1α and HIF-1β protein levels under hypoxic condition. SYP-5 inhibits tumor cell migration and invasion, as well as tumor angiogenesis.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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