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SML1941 Sigma-Aldrich

CGP3466B maleate salt

≥98% (HPLC)

Synonym: CGP 3466B, Dibenz[b,f]oxepin-10-methanamine, N-methyl-N-2-propyn-1-yl-, (2Z)-2-butenedioate (1:1), N-(Dibenz[b,f]oxepin-10-ylmethyl)-N-methyl-N-(2-propynyl)amine monomaleic acid salt, Omigapil maleate salt, TCH346

  • CAS Number 200189-97-5

  • Empirical Formula (Hill Notation) C19H17NO · C4H4O4

  • Molecular Weight 391.42

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Properties

assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 2 mg/mL, clear
storage temp.   2-8°C

Description

Biochem/physiol Actions

CGP3466B, also known as Omigapil maleate and TCH346, is a potent inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH). It has been shown to have neuroprotective activity and received U.S. FDA Fast Track Designation for the treatment of congenital muscular dystrophy in May 2016.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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