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SML2146 Sigma

SR-18292 Maleate

≥98% (HPLC)

Synonym: 1-[(1,1-Dimethylethyl)[(4-methylphenyl)methyl]amino]-3-(1H-indol-4-yloxy)-2-propanol maleate, SR 18292 maleate, SR 18292, SR-18292 Maleate

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Properties

assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 2 mg/mL, clear
storage temp.   2-8°C

Description

Biochem/physiol Actions

SR-18292 is a potent and specific inhibitor of hepatic gluconeogenesis via increased acetylation of PGC-1α and suppression of gluconeogenic gene expression. SR-18292 reduces blood glucose and increases hepatic insulin sensitivity in mouse models of T2D.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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