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SML2156 Sigma-Aldrich

Erlotinib hydrochloride

≥98% (HPLC)

Synonym: 774 hydrochloride, CP-358, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride, OSI-744 hydrochloride

  • CAS Number 183319-69-9

  • Empirical Formula (Hill Notation) C22H23N3O4 · HCl

  • Molecular Weight 429.90

  •  MDL number MFCD07781272

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, E
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white to beige
solubility   DMSO: 2 mg/mL, clear (warmed)
storage temp.   −20°C

Description

Biochem/physiol Actions

Erlotinib hydrochloride is an inhibitor of the receptor tyrosine kinase EGFR (epidermal growth factor receptor). It is used clinically for the treatment of non-small cell lung cancer (NSCLC) and in combination for metastatic pancreatic cancer.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
RTECS 
VA0971200

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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