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SRP6187 Sigma-Aldrich

Eosinophil Peroxidase human

≥95% (SDS-PAGE)

Synonym: EPER, EPO, EPP

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Properties

biological source   human
assay   ≥95% (SDS-PAGE)
form   lyophilized
mol wt   mol wt 70.5 kDa
packaging   pkg of 10 μg
storage condition   avoid repeated freeze/thaw cycles
UniProt accession no.   P11678
  P11678
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... EPX(8288)

Description

Reconstitution

Reconstitute in deionized H₂O. Aliquot and store at –20°C. Avoid freeze-thaw cycles.

Physical form

Lyophilized from 20 mM NaH2PO4, pH 7.5, and 150 mM NaCI.

General description

Native, human eosinophil peroxidase is a secreted hemoprotein that catalyzes oxidations of various substrates by hydrogen peroxide. Together with other leukocyte-derived enzymes, such as Myeloperoxidase, EPO plays an important role in the pathogenesis of asthma by mediating oxidative events that lead to the production of ROS (reactive oxygen species) and RNS (reactive nitrogen species).

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Protocols & Articles
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