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SRP6320 Sigma-Aldrich

FGF-12 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym: FGF12B, FHF1, Fibroblast growth factor 12

  •  NACRES NA.32

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Properties

Related Categories Cell Culture, FGF-9 to FGF-17, Fibroblast Growth Factors (FGF), Growth Factors and Cytokines, Reagents and Supplements More...
biological source   human
recombinant   expressed in E. coli
assay   ≥90% (SDS-PAGE)
form   liquid
mol wt   22.6 kDa (201 aa, 1-181 aa + His Tag)
packaging   pkg of 50 μg
concentration   1 mg/mL
UniProt accession no.   P61328 
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... FGF12(2257)

Description

General description

FGF12 (Fibroblast growth factor 12) is a member of the FGF superfamily of molecules which currently stands at 22 members. The FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF12 binds to IB2 (islet brain-2), a cellular kinase scaffold, and voltage gated sodium channels and also plays an important role in intracellular signaling and ion exchange. Recombinant human FGF12 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Physical form

1 mg/mL in 20 mM Tris pH 7.5, 10% glycerol, 1 mM DTT, 2 mM EDTA.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

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Fibroblast Growth Factors (FGFs) are potent regulators of cell proliferation, differentiation. They are critically important in normal development, tissue maintenance, wound repair and angiogenesis i...
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