SRP6353 Sigma-Aldrich

CD300A human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym: CD300a molecule, CLM-8, CMRF-35-H9, CMRF-35H, CMRF35-H9, CMRF35-H, CMRF35H9, CMRF35H, IGSF12, IRC1/IRC2, IRC1, IRC2, IRp60

  •  NACRES NA.32



Related Categories CD160 to CD340, Cell Biology, Cell Signaling and Neuroscience, Cluster of Differentiation (CD) Proteins, Cytokines and Growth Factors,
biological source   human
recombinant   expressed in E. coli
assay   ≥90% (SDS-PAGE)
form   liquid
mol wt   14.7 kDa (134 aa, 18-128 aa + His Tag)
packaging   pkg of 50 μg
concentration   0.5 mg/mL
UniProt accession no.   Q9UGN4
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... CD300a(11314)


General description

CD300A belongs to the CD300 family and contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Recombinant human CD300A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Physical form

0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol and 1 mM DTT.

Safety & Documentation

Safety Information

NONH for all modes of transport


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