EMAIL THIS PAGE TO A FRIEND
SRP6354 Sigma-Aldrich

CD3E human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym: T-cell surface glycoprotein CD3 epsilon chain, T3E, TCRE

  •  NACRES NA.32

Purchase

Properties

Related Categories CD1 to CD48, Cell Biology, Cell Signaling and Neuroscience, Cluster of Differentiation (CD) Proteins, Cytokines and Growth Factors,
biological source   human
recombinant   expressed in E. coli
assay   ≥90% (SDS-PAGE)
form   liquid
mol wt   14.1 kDa (127 aa, 23-126 aa + His Tag)
packaging   pkg of 50 μg
concentration   1 mg/mL
UniProt accession no.   P07766
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... CD3E(916)

Description

General description

CD3E is the CD3-epsilonpolypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor α/β and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. Recombinant human CD3E protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Physical form

1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, and 10% glycerol.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?