EMAIL THIS PAGE TO A FRIEND
SRP6368 Sigma-Aldrich

TREM2 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym: Trem2a, Trem2b, Trem2c, Triggering receptor expressed on myeloid cells 2

  •  NACRES NA.32

Purchase

Properties

biological source   human
recombinant   expressed in E. coli
assay   ≥90% (SDS-PAGE)
form   liquid
mol wt   20.4 kDa (181 aa, 19-161 aa + His Tag)
packaging   pkg of 50 μg
concentration   0.25 mg/mL
UniProt accession no.   Q9NZC2
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... TREM2(54209)

Description

General description

TREM2 is a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The protein functions in immune response and maybe involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. Recombinant human TREM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Physical form

0.25 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 1 mM DTT and 10% glycerol.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?