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T3397 Sigma-Aldrich

Tylosin solution

8 mg/mL in 0.9% NaCl, sterile-filtered, BioReagent, suitable for cell culture

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Properties

Related Categories Antibacterial, Antibiotic Solutions, Antibiotics, Antibiotics A to Z, Antibiotics T-Z,
InChI Key   ICVKYYINQHWDLM-KBEWXLTPSA-N
sterility   sterile-filtered
product line   BioReagent
form   solution
concentration   8 mg/mL in 0.9% NaCl
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, tested
color   colorless to yellow
suitability   suitable for cell culture
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-positive bacteria
  mycoplasma
storage temp.   2-8°C

Description

General description

Chemical structure: macrolide

Application

Tylosin is a mcrolide antibiotic commonly used in veterinary medicine. It has been used to study protein synthesis at the 50S ribosome, implant site abscess prevention in cattle, disposition kinetics and Mycoplasma gallisepticum and Mycoplasma meleagridis infections. This solution is recommended for use at 1 mL/L.

Biochem/physiol Actions

Mode of Action: Tylosin inhibits bacterial protein synthesis by binding to the 50S (L27 protein) ribosome.

Antimicrobial Spectrum: This product acts against gram-positive bacteria and mycoplasma.

Packaging

20ML

Preparation Note

This product was formulated to contain 8 mg/ml tylosin in 0.9% sodium chloride.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

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Request a Serum Sample

Cell Culture Guide
Protocols & Articles

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Peer-Reviewed Papers
15

References

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