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T4196 SAFC

L-Tryptophan

PharmaGrade, Ajinomoto, EP, JP, USP, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, suitable for cell culture

Synonym: (S)-2-Amino-3-(3-indolyl)propionic acid, L-α-Amino-3-indolepropionic acid

  • CAS Number 73-22-3

  • Empirical Formula (Hill Notation) C11H12N2O2

  • Molecular Weight 204.23

  •  Beilstein/REAXYS Number 86197

  •  EC Number 200-795-6

  •  MDL number MFCD00064340

  •  PubChem Substance ID 57654669

  •  NACRES NA.26

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Properties

Related Categories Amino Acids, Amino acids, Analytical/Chromatography, Biochemicals and Reagents, Cell Biology,
biological source   non-animal source
Agency/Method   EP
  JP
  USP
product line   PharmaGrade
assay   ≥98.5%
form   crystalline powder
mfr. no.   Ajinomoto
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, heavy metals, residual solvents, tested
mp   280-285 °C (dec.) (lit.)
solubility   1 M HCl: 10 mg/mL
Featured Industry   Pharmaceutical (small molecule)
foreign activity   cytotoxicity, tested
SMILES string   N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
InChI   1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
InChI key   QIVBCDIJIAJPQS-VIFPVBQESA-N

Description

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.
To request the Enhanced Quality Product Documentation for this product, please contact Customer Support and select ‘Product Documentation’. Please note that access to the Enhanced Quality Product Documentation for this product requires a confidentiality disclosure agreement.

Application

L-Tryptophan is an essential amino acid. It is naturally found in animal and plant protein. It can be used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Other Notes

Amino acid precursor of serotonin and melatonin

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

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Peer-Reviewed Papers
15

References

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