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T4443 Sigma-Aldrich

Tyrphostin AG 527

≥98%

Synonym: (−)-(R)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide, Tyrphostin B44

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Properties

assay   ≥98%
potency   IC50 (0.4 micromolar)
solubility   DMSO or ethanol: soluble
  DMSO: soluble
  ethanol: soluble
storage temp.   −20°C
Gene Information   human ... MST1R(4486), PTK2(5747), PTK6(5753), PTK7(5754), TWF1(5756), TXK(7294)

Description

Application

Tyrphostin AG 527 has been used as a tyrosine kinase inhibitor to study its effect on PGE2-induced contractions in rabbit duodenum4.

Biochem/physiol Actions

Protein tyrosine kinase inhibitor similar to Tyrphostin AG 494

Preparation Note

Tyrphostin AG 527 is soluble in DMSO and ethanol.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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