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T5080 Sigma-Aldrich

Thymulin

lyophilized powder

Synonym: Pyr-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH trifluoroacetate salt, STF, Serum Thymic Factor

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Immunomodulators,
InChI Key   LIFNDDBLJFPEAN-BPSSIEEOSA-N
form   lyophilized powder
color   white
solubility   deionized water: soluble
shipped in   dry ice
storage temp.   −20°C

Description

Amino Acid Sequence

Glp-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn

Application

Thymulin was used to study the impact of this compound on gonadotrophin-induced ovulation and on onset of puberty in mice.

Biochem/physiol Actions

Thymulin also refers as serum thymic factor is a nonapeptide that reduces the hyperalgesia induced due to peripheral endotoxin administration in rats and mice. It also possesses an immunomodulator function by regulating the cytokine production by peripheral blood mononuclear cells (PBMC).

Thymulin, also known as Thymic Factor, is a nonapeptide produced by epithelial cell popuation in the thymus. This peptide is known for its immunomodulatory role and has neuroendocrine effects as well.

Physical form

Lyophilized from 0.1% aqueous TFA.

Other Notes

Lyophilized from 0.1% TFA in H2O

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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