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T6068 Sigma-Aldrich

Tyrphostin AG 1024

≥98%, solid

  • CAS Number 65678-07-1

  • Empirical Formula (Hill Notation) C14H13BrN2O

  • Molecular Weight 305.17

  •  MDL number MFCD02179365

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Properties

assay   ≥98%
form   solid
potency   0.4 μM IC50
color   yellow
solubility   DMSO: soluble
  ethanol: insoluble
storage temp.   −20°C

Description

Application

Tyrphostin AG 1024 has been used to block IGF-IR during the analysis of IGF-I signaling in siSphK1 cells3. AG-1024 has also been used to study IGF-I-induced collagen synthesis in human dermal fibroblasts4.

Biochem/physiol Actions

IGF-1 receptor inhibitor

Preparation Note

Tyrphostin AG 1024 is soluble in DMSO and ethanol.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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