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T7450 Sigma-Aldrich

T62

≥98% (HPLC), crystalline

Synonym: 2-Amino-3-(4-chlorobenzoyl)-5,6,7,8-tetrahydrobenzothiophene

  • CAS Number 40312-34-3

  • Empirical Formula (Hill Notation) C15H14ClNOS

  • Molecular Weight 291.80

  •  MDL number MFCD02738687

  •  PubChem Substance ID 24724635

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Properties

Related Categories Adenosines/P2 Nucleotide Receptors (Purinergics), Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   OTZVBZFYMFTYKH-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   crystalline
color   orange
solubility   DMSO: ~20 mg/mL
  H2O: insoluble
storage temp.   2-8°C
Gene Information   human ... ADORA1(134)

Description

Biochem/physiol Actions

Studies in carrageenin-inflamed rats have reported that T62 can reverse thermal hypersensitivity. T62 has also been reported to reduce mechanical allodynia and induce drug tolerance over time in rat models of neuropathic pain.

Allosteric enhancer of A1 adenosine receptor.

Preparation Note

T62 is soluble in DMSO at approximately 20 mg/ml and is insoluble in water.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Making Headway

Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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