T8441 Sigma-Aldrich


from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

Synonym: (2S,3R)-2-Amino-3-hydroxybutyric acid

  • CAS Number 72-19-5

  • Linear Formula CH3CH(OH)CH(NH2)CO2H

  • Molecular Weight 119.12

  •  Beilstein/REAXYS Number 1721646

  •  EC Number 200-774-1

  •  MDL number MFCD00064270

  •  eCl@ss 32160406

  •  PubChem Substance ID 24900531

  •  NACRES NA.26



Related Categories Allium cepa (Onion), Allium sativum (Garlic), Aloe Vera, Amino Acids, Amino Acids & Derivatives,
Quality Level   200
biological source   non-animal source
Agency/Method   meets EP testing specifications
  meets JP testing specifications
  meets USP testing specifications
assay   99.0-101.0%
form   powder
quality   meets EP, JP, USP testing specifications
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, tested
color   white
mp   256 °C (dec.) (lit.)
solubility   H2O: 1 g/10 mL, clear, colorless
Featured Industry   Pharmaceutical (small molecule)
SMILES string   C[C@@H](O)[C@H](N)C(O)=O
InChI   1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1


General description

L-Threonine is a naturally occurring amino acid belonging to the aspartate family of amino acids.


L-Threonine has been used for the following :
• To study the effect of heat on homoserine kinase activity
• In Plackett–Burman analysis and then to study the effect of selected amino acids on monoclonal antibody production in CHO cells
• As a substrate to determine the L-threonine dehydrogenase activity
• To study the effect of L-Threonine on the growth rate of P. putida, to check for its tolerance towards L-Threonine


1 kg in poly bottle

10 mg in glass bottle

25, 100 g in poly bottle

Biochem/physiol Actions

L-Threonine is considered to be an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-Threonine is required for the performance of the immune system. It is also essential for O-linked glycosylation, protein phosphorylation and glycine synthesis.

Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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