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T9907 Sigma-Aldrich

Thyrocalcitonin from chicken

≥97% (HPLC)

Synonym: Calcitonin, Cys-Ala-Ser-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 [Disulfide bridge: 1–7]

  • CAS Number 100016-62-4

  • Empirical Formula (Hill Notation) C145H240N42O46S2

  • Molecular Weight 3371.84

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Properties

assay   ≥97% (HPLC)
storage temp.   −20°C

Description

Biochem/physiol Actions

Hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes.

Other Notes

A 32 amino acid polypeptide, 8 of which are conserved across all species.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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