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U6883 Sigma-Aldrich

cis-Urocanic acid

≥98% (HPLC), solid (fluffy)

Synonym: cis-3-(1H-imidazol-4-yl)-2-propenoic acid, cis-UCA

  • CAS Number 7699-35-6

  • Empirical Formula (Hill Notation) C6H6N2O2

  • Molecular Weight 138.12

  •  MDL number MFCD11045310

  •  PubChem Substance ID 329827646

  •  NACRES NA.77

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Properties

Related Categories Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   LOIYMIARKYCTBW-UPHRSURJSA-N
assay   ≥98% (HPLC)
form   solid (fluffy)
storage condition   protect from light
color   white
solubility   H2O: >10 mg/mL
storage temp.   −20°C

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

cis-Urocanic acid, a 5-HT agonist, is a product of uv isomerization of trans-urocanic acid in skin, which leads to immunosuppression via activation of 5-HT2A receptor.

Preparation Note

cis-Urocanic acid is soluble in water at a concentration that is greater than 10 mg/ml.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Serotonin Receptors

Serotonin (5-hydroxytryptamine, 5-HT) is widely distributed throughout the mammalian body, being synthesized from L-tryptophan in enterochromaffin cells of the gastro-intestinal tract as well as in s...
Keywords: Active transport, Atomic absorption spectroscopy, Cancer, Clinical, Gene expression, Ligands, Neurotransmitters, Obesity, Polymorphisms, Schizophrenia, Transduction

Peer-Reviewed Papers
15

References

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