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V1255 Sigma-Aldrich

D-Valine

suitable for cell culture, BioReagent

Synonym: (R)-α-Aminoisovaleric acid, D-2-Amino-3-methylbutanoic acid

  • CAS Number 640-68-6

  • Linear Formula (CH3)2CHCH(NH2)CO2H

  • Molecular Weight 117.15

  •  Beilstein/REAXYS Number 1721135

  •  EC Number 211-368-9

  •  MDL number MFCD00064219

  •  PubChem Substance ID 24900713

  •  NACRES NA.75

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Properties

Related Categories Amino Acids, Amino Acids and Vitamins, Asymmetric Synthesis, Cell Culture, Chemical Synthesis,
InChI Key   KZSNJWFQEVHDMF-SCSAIBSYSA-N
product line   BioReagent
application(s)   cell culture | mammalian: suitable
mp   >295 °C (subl.) (lit.)

Description

General description

L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine.

Application

D-valine is used in cell culture as a selective inhibitor of cell proliferation, wherein it inhibits cells that lack the enzyme D-amino acid oxidase. Historically D-valine has been used to inhibit fibroblast growth while allowing selective growth of epithelial cells.

Packaging

1, 5, 25 g in poly bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
YV9360000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

HPLC Analysis of Valine Enantiomers on Astec® CHIROBIOTIC® T (Formic Acid Mobile Phase Additive)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Valine Enantiomers on Astec® CHIROBIOTIC® T (Formic Acid Mobile Phase Additive)
Keywords: Chromatography, High performance liquid chromatography

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Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
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Peer-Reviewed Papers
15

References

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