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A0138 Sigma-Aldrich

Aflatoxin G1

from Aspergillus flavus

  • CAS Number 1165-39-5

  • Empirical Formula (Hill Notation) C17H12O7

  • Molecular Weight 328.27

  •  Beilstein/REAXYS Number 1299768

  •  EC Number 214-615-9

  •  MDL number MFCD00005089

  •  PubChem Substance ID 24890402

  •  NACRES NA.77

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Properties

Related Categories A-AM, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cancer Research, Carcinogens,
Quality Level   200
biological source   Aspergillus flavus
storage temp.   2-8°C
SMILES string   COc1cc2OC3OC=CC3c2c4OC(=O)C5=C(CCOC5=O)c14
InChI   1S/C17H12O7/c1-20-9-6-10-12(8-3-5-22-17(8)23-10)14-11(9)7-2-4-21-15(18)13(7)16(19)24-14/h3,5-6,8,17H,2,4H2,1H3
InChI key   XWIYFDMXXLINPU-UHFFFAOYSA-N

Description

General description

Aflatoxins are hepatotoxic metabolites, that are produced by molds, such as, Aspergillus flavus and Aspergillus parasiticus. They are naturally occurring poisonous carcinogens and the most widely known mycotoxins. They are associated with liver cancer and immune system suppression.

Application

Aflatoxin G1 from Aspergillus flavus has been used as a standard for the determination of aflatoxin in various samples.

Biochem/physiol Actions

Hepatocarcinogen. Food contaminant produced by Aspergillus flavus, a common soil fungus.

Warning

Possibly carcinogenic.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3462 6.1 / PGI
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Biofiles, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Events, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Sequences, Transcription, Type, transformation

HPLC Analysis of Aflatoxin Analogs on Ascentis® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Aflatoxin Analogs on Ascentis® C18
Keywords: Chromatography, High performance liquid chromatography

UHPLC-MS/MS Analysis of µLtiple Mycotoxins on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC-MS/MS Analysis of µLtiple Mycotoxins on Titan™ C18
Keywords: Chromatography, Clinical, Mass spectrometry

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Peer-Reviewed Papers
15

References

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