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A0278 Sigma-Aldrich

L-Ascorbic acid

reagent grade

Synonym: L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

  • CAS Number 50-81-7

  • Empirical Formula (Hill Notation) C6H8O6

  • Molecular Weight 176.12

  •  Beilstein/REAXYS Number 84272

  •  EC Number 200-066-2

  •  MDL number MFCD00064328

  •  PubChem Substance ID 24890417

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Properties

Related Categories Antioxidant and Free Radical Scavengers, Cancer Research, Cell Biology, Chemopreventive Agents, Core Bioreagents,
biological source   synthetic
grade   reagent grade
assay   ≥98% (with Iodine, titration)
form   powder
application(s)   HPLC: suitable
color   white to light yellow
pH   1.0-2.5 (25 °C, 176 g/L in water)
mp   190-194 °C (dec.)
solubility   water: soluble 50 mg/mL
storage temp.   room temp
SMILES string   OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
InChI   1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChI key   CIWBSHSKHKDKBQ-JLAZNSOCSA-N
Gene Information   human ... SLC23A2(9962)

Description

General description

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. It is a water-soluble vitamin.

Application

L-Ascorbic acid has been used as a standard in high performance liquid chromatography (HPLC) for quantification of L-ascorbic acid.

L-Ascorbic acid may be used as standard in assay for erythrocyte hemolysis mediated by peroxyl free radicals. It may be used for the reduction of graphene oxide sheets.

Packaging

1 kg in glass bottle

25, 100, 500 g in glass bottle

Biochem/physiol Actions

L-Ascorbic acid is an anti-oxidant. L-Ascorbic acid (vitamin C) is important for many enzymatic reactions for maintaining prosthetic metal ions in their reduced forms (for example, Fe2+, Cu+). It protects tissues from oxidative damage by scavenging free radicals. It has mild reductive ability and nontoxic property. It is commonly employed reductant in the laboratory. Colorimetric determination of ascorbic acid in plasma using acid phosphotungstate has been reported.

L-ascorbic acid modified poly(ester urethane)s might facilitate soft tissue regeneration. It also helps in increasing iron absorption by tissues. In addition, it aids in tyrosine metabolism and microsomal drug metabolism.

Caution

May darken in storage.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
CI7650000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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