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  • A1719 - Monoclonal Anti-Activin A βA subunit antibody produced in mouse

A1719 Sigma

Monoclonal Anti-Activin A βA subunit antibody produced in mouse

clone 69403.11, purified immunoglobulin, lyophilized powder



Related Categories AC-AC, Activins, Activins and Inhibins, Alphabetical Index, Antibodies,
species reactivity   human
application(s)   capture ELISA: suitable
  neutralization: suitable
clone   69403.11, monoclonal
antibody form   purified immunoglobulin
form   lyophilized powder
isotype   IgG1
storage temp.   −20°C
Gene Information   human ... INHBA(3624)
biological source   mouse
recombinant   expressed in mouse cell line
conjugate   unconjugated



mature recombinant human activin A.

General description

Activins are members of the TGF-β family. Activins are dimeric proteins composed of 2 beta subunits. Acitivn A contains 2 β A subunits. Activins bind to the Type II Activin receptor triggering phosphorylation of Type I Acitivn receptor (ALK4) and activation of downstream pathways such as proliferation and apoptosis.

Monoclonal anti-activin A βA subunit antibody can neutralize the bioactivity of recombinant human activin A. It also recognizes activin A precursors. Furthermore, the antibody binds to activin A βA subunit and inhibin A βA subunit by capture ELISA.

Physical form

Lyophilized from a solution of phosphate buffered saline with 5% trehalose

Preparation Note

Purified using protein G


Monoclonal anti-activin A betaA subunit is suitable for use in capture ELISA and neutralization assays.

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Certificate of Analysis

Certificate of Origin

Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  2
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