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A1774 Sigma-Aldrich

Amikacin disulfate salt

potency: 674-786 μg per mg (as amikacin base)

  • CAS Number 39831-55-5

  • Empirical Formula (Hill Notation) C22H43N5O13 · 2H2SO4

  • Molecular Weight 781.76

  •  Beilstein Registry Number 6172633

  •  EC Number 254-648-6

  •  MDL number MFCD00167475

  •  PubChem Substance ID 24890586

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Properties

Related Categories A - K, Aminoglycosides, Antibacterial, Antibiotics, Antibiotics A to Z,
biological source   synthetic
InChI Key   FXKSEJFHKVNEFI-GCZBSULCSA-N
form   powder
potency   674-786 μg per mg (as amikacin base)
color   white to off-white
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  mycobacteria
storage temp.   2-8°C

Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria . It is used to study organism-directed delivery of antibiotics as well as drug resistance .

Biochem/physiol Actions

Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.

General description

Chemical structure: aminoglycoside

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
WK1961200
Protocols & Articles
Peer-Reviewed Papers
15

References

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