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A2099 Sigma-Aldrich

N-Acetyl-Leu-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin

≥95% (HPLC), solid

Synonym: Ac-LEVD-AFC

  • Empirical Formula (Hill Notation) C32H40N5O11F3

  • Molecular Weight 727.68

  •  MDL number MFCD01862605

  •  PubChem Substance ID 329770729

  •  NACRES NA.32

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Properties

Related Categories Apoptosis Enzymes, Apoptosis and Cell Cycle, Application Index, Biochemicals and Reagents, Caspase 4,
Quality Level   200
assay   ≥95% (HPLC)
form   solid
storage temp.   −20°C
SMILES string   CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(OC(=O)C=C2C(F)(F)F)c1
InChI   1S/C32H40F3N5O11/c1-14(2)10-21(36-16(5)41)30(49)38-20(8-9-24(42)43)28(47)40-27(15(3)4)31(50)39-22(13-25(44)45)29(48)37-17-6-7-18-19(32(33,34)35)12-26(46)51-23(18)11-17/h6-7,11-12,14-15,20-22,27H,8-10,13H2,1-5H3,(H,36,41)(H,37,48)(H,38,49)(H,39,50)(H,40,47)(H,42,43)(H,44,45)/t20-,21-,22-,27-/m0/s1
InChI key   FETZKXHXYOHAAN-LFYAFONDSA-N
Gene Information   rat ... Prkcq(85420)

Description

Amino Acid Sequence

NAc-Leu-Glu-Val-Asp-AFC

Biochem/physiol Actions

Fluorogenic substrate for caspase 4.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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