• USA Home
  • A2388 - N-Acetylneuraminic acid

EMAIL THIS PAGE TO A FRIEND
A2388 Sigma-Aldrich

N-Acetylneuraminic acid

from Escherichia coli, ≥98%

Synonym: 5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid, Lactaminic acid, NAN, NANA, Sialic acid

  • CAS Number 131-48-6

  • Empirical Formula (Hill Notation) C11H19NO9

  • Molecular Weight 309.27

  •  Beilstein/REAXYS Number 1716283

  •  EC Number 205-023-1

  •  MDL number MFCD00006620

  •  PubChem Substance ID 24890650

Purchase

Properties

Related Categories Biochemicals and Reagents, Carbohydrate, Carbohydrates, Carbohydrates A to Z, Carbohydrates A-C,
Quality Level   300
biological source   Escherichia coli
type   Type VI
assay   ≥98%
form   powder
optical activity   [α]20/D -34.0 to -30.0 °, c = 1% in water
application(s)   HPLC: suitable
mp   184-186  °C
storage temp.   −20°C
SMILES string   O[C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@@H]([C@@H](CO)O)O)C(O)=O
InChI   1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11-/m0/s1
InChI key   SQVRNKJHWKZAKO-PFQGKNLYSA-N

Description

Application

N-Acetylneuraminic acid (NANA, Neu5Ac) is a major component of glycoconjugates such as glycolipids, glycoproteins and proteoglycans (sialogylcoproteins) where it confers selective binding characteristics to the glycosylated component. Neu5Ac is used to study its biochemistry, metabolism and uptake in vivo and in vitro. Neu5Ac is used in the development of nanocarriers.

Packaging

1 g in poly bottle

25, 100, 250 mg in poly bottle

10 mg in glass bottle

Biochem/physiol Actions

Both sialic acid and neuraminic acid are loosely used to refer to conjugates of neuraminic acid. N-Acetylneuraminic acid is often found as the terminal sugar of cell surface glycoproteins. Cell surface glycoproteins have important roles in cell recognition and interaction as well as in cell adhesion. Membrane glycoproteins are also important in tumor growth and metastases.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles

Protocols

Enzymatic Assay of Neuraminidase

2.1. This procedure applies to products that have a specification for neuraminidase content by enzymatic determination.

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?