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A2388 Sigma

N-Acetylneuraminic acid

from Escherichia coli, ≥98%

Synonym: 5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid, Lactaminic acid, NAN, NANA, Sialic acid

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Properties

Related Categories Biochemicals and Reagents, Carbohydrate, Carbohydrates, Carbohydrates A to Z, Carbohydrates A-C,
Quality Level   PREMIUM
biological source   from Escherichia coli
InChI Key   SQVRNKJHWKZAKO-PFQGKNLYSA-N
type   Type VI
assay   ≥98%
storage temp.   −20°C

Description

Biochem/physiol Actions

Both sialic acid and neuraminic acid are loosely used to refer to conjugates of neuraminic acid. N-Acetylneuraminic acid is often found as the terminal sugar of cell surface glycoproteins. Cell surface glycoproteins have important roles in cell recognition and interaction as well as in cell adhesion. Membrane glycoproteins are also important in tumor growth and metastases.

Packaging

1 g in poly bottle

25, 100, 250 mg in poly bottle

10 mg in glass bottle

Application

N-Acetylneuraminic acid (NANA, Neu5Ac) is a major component of glycoconjugates such as glycolipids, glycoproteins and proteoglycans (sialogylcoproteins) where it confers selective binding characteristics to the glycosylated component. Neu5Ac is used to study its biochemistry, metabolism and uptake in vivo and in vitro. Neu5Ac is used in the development of nanocarriers.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Protocols

Enzymatic Assay of Neuraminidase

2.1. This procedure applies to products that have a specification for neuraminidase content by enzymatic determination.

Peer-Reviewed Papers
15

References

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