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A2661 Sigma-Aldrich

Acetylcholine chloride

suitable for cell culture

Synonym: ACh

  • CAS Number 60-31-1

  • Linear Formula (CH3)3N+CH2CH2OCOCH3Cl-

  • Molecular Weight 181.66

  •  Beilstein/REAXYS Number 3571875

  •  EC Number 200-468-8

  •  MDL number MFCD00011698

  •  eCl@ss 32190102

  •  PubChem Substance ID 24890686

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Description

Biochem/physiol Actions

Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergic anti-inflammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
FZ9800000

Documents

Certificate of Analysis

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Certificate of Origin

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Cell Culture Guide
Protocols & Articles

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Peer-Reviewed Papers
15

References

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