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  • A2726 - Anti-ADAM-10, C-terminal antibody produced in rabbit

A2726 Sigma-Aldrich

Anti-ADAM-10, C-terminal antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-A Disintegrin And Metalloproteinase-10, Anti-Kuzbanian, Anti-MADM



General description

ADAM is a member of the A Distintegrin and Metalloproteinase family of proteins which possess both adhesion and zinc protease functions. ADAM-10 is a sheddase with both a secreted and membrane-bound form. ADAM-10 null mice are embryonically lethal with nural and cardiac defects.

In immunoblotting, an 80-85 kDa band can be detected, which may represent the precursor proform. A 60 kDa faint band may be detected in some cell lines including Jurkat, which appears to be the processed mature protein. Also, bands at below 50 kDa may be seen.


synthetic peptide corresponding to amino acids 732-748 of human ADAM-10. The sequence is identical to bovine and rat and differs by one amino acid in mouse.


Rabbit anti-ADAM-10, C-terminal antibody can be used for immunoblotting assays at dilutions ranging from 1:500-1:2,000.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety & Documentation

Safety Information

NONH for all modes of transport


Certificate of Analysis

Certificate of Origin

Milli-Q® Water Purification Solutions
Protocols & Articles


Antibody Basics

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Western Blot Protocol | Immunoblotting Protocol

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