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A2786 Sigma-Aldrich

Adenine

BioReagent, suitable for cell culture

Synonym: 6-Aminopurine, Vitamin B4

  • CAS Number 73-24-5

  • Empirical Formula (Hill Notation) C5H5N5

  • Molecular Weight 135.13

  •  Beilstein/REAXYS Number 5777

  •  EC Number 200-796-1

  •  MDL number MFCD00041790

  •  PubChem Substance ID 24890691

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Properties

Related Categories Biochemicals and Reagents, Cell Culture, Miscellaneous Reagents and Supplements, Reagents and Supplements, Vitamin B,
InChI Key   GFFGJBXGBJISGV-UHFFFAOYSA-N
product line   BioReagent
assay   ≥99%
form   powder
mol wt   Mw 135.13 g/mol
application(s)   cell culture | mammalian: suitable
color   white to off-white
mp   >360 °C (lit.)
solubility   0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow
suitability   suitable for cell culture
Gene Information   human ... AKT1(207), GSK3B(2932), LCK(3932), MAP3K1(4214), MAPK14(1432), MAPK8(5599), MAPK9(5601), MAPKAPK2(9261), PRKACA(5566), PRKCA(5578), RAF1(5894), ROCK2(9475)
mouse ... Mapk1(26413)
rat ... Camk2a(25400), Mapk10(25272)

Description

General description

Adenine is a purine nucleobase, synthesized from inosine monophosphate(IMP). It is a nitrogenous heterocyclic aromatic compound.

Application

Adenine has been used:
• a component of green medium used for the derivation of keratinocytes from plucked hair follicles
• for the serial culture of adult murine keratinocytes
• as a media component for SSEA4+ limbal stromal stem cell differentiation

Packaging

5, 25, 100 g in poly bottle

Biochem/physiol Actions

Adenine is a component of important biomolecules such as adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). NAD and FAD forms the structure of DNA and RNA, and plays important role in protein synthesis. ATP is an energy source, that is essential for cellular respiration.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
AU6125000

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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