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  • A4034 - (+)-Sodium L-ascorbate

A4034 Sigma-Aldrich

(+)-Sodium L-ascorbate

powder, BioReagent, suitable for cell culture

Synonym: L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt

  • CAS Number 134-03-2

  • Empirical Formula (Hill Notation) C6H7NaO6

  • Molecular Weight 198.11

  •  Beilstein/REAXYS Number 3767246

  •  EC Number 205-126-1

  •  MDL number MFCD00082340

  •  eCl@ss 34058010

  •  PubChem Substance ID 24890738

  •  NACRES NA.75



Related Categories Amino Acids and Vitamins, Bioactives and Supplements for Stem Cell Expansion, Bioactives/Supplements, Cell Biology, Cell Culture,
Quality Level   200
biological source   synthetic (organic)
product line   BioReagent
assay   ≥98%
form   powder
mol wt   Mw 135.13 g/mol
application(s)   cell culture | mammalian: suitable
  cell culture | plant: suitable
color   white to off-white
mp   220 °C (dec.) (lit.)
solubility   H2O: 50 mg/mL
SMILES string   [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]
InChI   1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1


General description

(+)-Sodium L-ascorbate (SA) is a potential antioxidant and is a derivative of vitamin C (L-ascorbic acid). It is widely used as a food additive. In addition, SA enhances growth retardation activity of bleomycin sulfate, R020-1724 (an inhibitor of cyclic nucleotide phosphodiesterase), prostaglandin E1 and sodium butyrate agents on neuroblastoma cells in culture. Elevated levels of SA induces two-stage urinary bladder carcinogenesis in rats. sodium L-ascorbate in combination with collagenogenesis inhibitors is used to treat dermal scars and keloids.


(+)-Sodium L-ascorbate has been used:
• to produce H2O2 in cell culture media
• as a reducing agent for a cell-permeable artificial electron donor, N,N,N′,N′-tetramethyl-p-phenylenediamine (TMPD)
• to study its effect on production of collagen and elastic fibers in fibroblasts cultures derived from normal human skin and dermal fat

Used for preparation of plant extracts; reductant for the isolation of chloroplasts.


1 kg in poly bottle

100, 500 g in poly bottle

Biochem/physiol Actions


Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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