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A4237 Sigma-Aldrich

Cefuroxime Axetil

Synonym: [6R-[6α,7β(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-(acetyloxy)ethyl ester

  • CAS Number 64544-07-6

  • Empirical Formula (Hill Notation) C20H22N4O10S

  • Molecular Weight 510.47

  •  MDL number MFCD00864991

  •  PubChem Substance ID 329770853

  •  NACRES NA.85

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Properties

assay   ≥98% (HPLC)
form   powder
color   white to off-white
solubility   DMSO: 1 mg/mL
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   −20°C
SMILES string   O=C1[C@@H](NC(/C(C2=CC=CO2)=N\OC)=O)[C@]3([H])N1C(C(OC(C)OC(C)=O)=O)=C(COC(N)=O)CS3
InChI   1S/C20H22N4O10S/c1-9(25)33-10(2)34-19(28)15-11(7-32-20(21)29)8-35-18-14(17(27)24(15)18)22-16(26)13(23-30-3)12-5-4-6-31-12/h4-6,10,14,18H,7-8H2,1-3H3,(H2,21,29)(H,22,26)/b23-13-/t10?,14-,18-/m1/s1
InChI key   KEJCWVGMRLCZQQ-YJBYXUATSA-N

Description

Packaging

100 mg in poly bottle

Biochem/physiol Actions

Cefuroxime axetil is acetoxyethyl pro-drug cephalosporin with activity against some strains of β-lactamase producing bacteria. It is a broad spectrum antibiotic active against Gram-positive and Gram-negative bacteria.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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