EMAIL THIS PAGE TO A FRIEND
A4474 SAFC

L-Arginine

PharmaGrade, Ajinomoto, EP, USP, manufactured under appropriate GMP controls for Pharma or Biopharmaceutical production, suitable for cell culture

Synonym: (S)-2-Amino-5-guanidinopentanoic acid

  • CAS Number 74-79-3

  • Linear Formula H2NC(=NH)NH(CH2)3CH(NH2)CO2H

  • Molecular Weight 174.20

  •  Beilstein/REAXYS Number 1725413

  •  EC Number 200-811-1

  •  MDL number MFCD00002635

  •  eCl@ss 32160406

  •  PubChem Substance ID 57653850

  •  NACRES NA.26

Purchase

Properties

Related Categories Amino Acids, Amino acids, Analytical/Chromatography, Biochemicals and Reagents, Cell Biology,
biological source   non-animal source
Agency/Method   EP
  USP
product line   PharmaGrade
assay   >98.5%
form   crystalline powder
mfr. no.   Ajinomoto
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, heavy metals, trace metals, residual solvents, tested
mp   222 °C (dec.) (lit.)
solubility   H2O: 100 mg/mL
suitability   suitable for manufacturing use
Featured Industry   Pharmaceutical (small molecule)
SMILES string   N[C@@H](CCCNC(N)=N)C(O)=O
InChI   1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
InChI key   ODKSFYDXXFIFQN-BYPYZUCNSA-N
Gene Information   human ... NOS1(4842), NOS2(4843)
rat ... Ppm1a(24666)

Description

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.
To request the Enhanced Quality Product Documentation for this product, please contact Customer Support and select ‘Product Documentation’. Please note that access to the Enhanced Quality Product Documentation for this product requires a confidentiality disclosure agreement.

Application

L-Arginine is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Related Content

Amino Acids Reference Charts

Amino acids are the compounds or building blocks that make up peptides and proteins. Each amino acid is structured from an amino group and a carboxyl group bound to a tetrahedral carbon. This carbon ...
Keywords: Building blocks, Gene expression, Mass spectrometry

Enhanced Quality Program [VIDEO]

The Enhanced Quality Program is a quality management system that is used to differentiate products based on the required level of transparency, control and documentation support determined by the nee...

One Quality Policy [VIDEO]

Sigma-Aldrich maintains one quality policy on a global level to provide consistency in vision, maintained across all manufacturing and distribution sites so that the company on the whole is adhering ...

Quality Management Systems [VIDEO]

See how we combine the use of various Quality Management Systems to manage manufacturing and supply chain for our products, as well as ensure data integrity for information provided to customers via ...

Risk Management [VIDEO]

Our Quality Policy means that we are able to provide certain information to end customers based on a product’s Enhanced Quality level, and that information is limited to what we are able to guarantee...

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?