• USA Home
  • A4730 - Amthamine dihydrobromide

EMAIL THIS PAGE TO A FRIEND
A4730 Sigma-Aldrich

Amthamine dihydrobromide

≥98% (HPLC), solid

Synonym: 2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide

  • CAS Number 142457-00-9

  • Empirical Formula (Hill Notation) C6H11N3S · 2HBr

  • Molecular Weight 319.06

  •  MDL number MFCD00673891

  •  PubChem Substance ID 24890905

  •  NACRES NA.77

Purchase

Properties

Related Categories A-AM, Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
Quality Level   100
assay   ≥98% (HPLC)
form   solid
color   off-white
solubility   H2O: 27 mg/mL
storage temp.   2-8°C
SMILES string   Br[H].Br[H].Cc1nc(N)sc1CCN
InChI   1S/C6H11N3S.2BrH/c1-4-5(2-3-7)10-6(8)9-4;;/h2-3,7H2,1H3,(H2,8,9);2*1H
InChI key   XFXNNOPUDSFVJE-UHFFFAOYSA-N

Description

Application

Amthamine dihydrobromide is a histamine H2 receptor agonist. Amthamine dihydrobromide has been used to study the effect of mast cells on T regulatory cell function.

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Amthamine dihydrobromide is a H2 histamine receptor agonist. Amthamine dihydrobromide, similar to histamine, inhibits H2 receptor-mediated eosinophil peroxidase (EPO) release with IC50 = 0.4 μM; a weak antagonist at H3 and shows no activity at H1 receptors.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?