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A5095 Sigma-Aldrich

N-Acetyl-Val-Glu-Ile-Asp-7-amido-4-trifluoromethylcoumarin

≥97% (HPLC), powder

Synonym: Ac-VEID-AFC

  • Linear Formula C32H40N5O11F3

  • Molecular Weight 727.68

  •  MDL number MFCD01318833

  •  PubChem Substance ID 329770866

  •  NACRES NA.32

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Properties

Related Categories Apoptosis Enzymes, Apoptosis and Cell Cycle, Application Index, Biochemicals and Reagents, Caspase 6,
Quality Level   200
assay   ≥97% (HPLC)
form   powder
solubility   DMSO/DMF: 20 mM
storage temp.   −20°C
SMILES string   CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3c(OC(=O)C=C3C(F)(F)F)c2
InChI   1S/C38H44F3N5O12/c1-5-20(4)32(36(55)44-26(17-29(49)50)34(53)42-22-11-12-23-24(38(39,40)41)16-30(51)58-27(23)15-22)45-33(52)25(13-14-28(47)48)43-35(54)31(19(2)3)46-37(56)57-18-21-9-7-6-8-10-21/h6-12,15-16,19-20,25-26,31-32H,5,13-14,17-18H2,1-4H3,(H,42,53)(H,43,54)(H,44,55)(H,45,52)(H,46,56)(H,47,48)(H,49,50)/t20-,25-,26-,31-,32-/m0/s1
InChI key   OEVAAZFKVRJQQH-UXAYAQJLSA-N
Gene Information   human ... CASP6(839)

Description

Amino Acid Sequence

NAc-Val-Glu-Ile-Asp-AFC

Biochem/physiol Actions

Fluorogenic substrate for caspase 6 (Mch-2α).

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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